Reinstall Office 2010 Home and Bussiness! (Also deleted the folders in C:/Users/Appdata/Local&Roaming/Microsoft/Office) Logging in with the user on another PC, he can open it from there. Logging in with another user on the laptop, this doesn't work. Options > Trust Center > Protected View > Uncheck all boxes. Options > Advanced > General > Uncheck 'Ignore other applications that use Dynamic Data Exchange (DDE))'
Created local account (with admin rights) When he tries to open it from the network drive, it gives the error message. When the user downloaded the file to his local drive, he can open it. This is with all the files on our network. We've also tried to open Excel first, then open it from the tab: File > Open. When we are doubling clicking the file, we're getting the message: 'Could not open \\.xlsx' Currently we're having a problem with an user who can't open excel (.xlsx) files from our network drives.